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분야 : 의약학 > 내과학
발행기관 : 대한신장학회
간행물정보 : Kidney Research and Clinical Practice(구 대한신장학회지), 2013 pp.138~141 (총 4pages)
 
 
영문초록
Idiopathic membranous nephropathy is a common cause of nephrotic syndrome, and has been reported as a cause of idiopathic primary glomerulonephropathy in up to 90% of patients. However, the treatment options remain controversial. We report two cases of idiopathic membranous nephropathy that were treated with rituximab. A 54-yearold man and a 64-year old man were admitted for rituximab therapy. They had previously been treated with combinations of immunosuppressive agents including cyclophosphamide, cyclosporine, mycophenolate, and steroids. However, the patients` heavy proteinuria was not resolved. Both patients received rituximab therapy, 2 weeks apart. After several months of follow-up and a second round of rituximab treatment for each patient, their proteinuria decreased and partial remission of disease was achieved in both patients.
 
 
Idiopathic membranous nephropathy, Nephrotic syndrome, Proteinuria, Rituximab
 
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