분야
pptx목차
NSAID의 작용기전
Links between hypoxia and inflammation
Prevalence : 0.5~1.9% of the general population
Asthmatic aspirin intolerance : 4.3~11%
With asthma and nasal polyposis : 25.6%
Chronic idiopathic urticaria(CIU) 환자에서 호발.
Risk factor
Female
Young adulthood
Atopy patient
Intermittent NSAID user
Links between hypoxia and inflammation
Acute reaction
Respiratory reaction
- Aspirin exacerbated respiratory disease
: nasal congestion, anosmia, chronic rhinosinusitis, nasal polyps which re-grow rapidly after surgery. Progress to Asthma.
Urticaria and angioedema in CIU patient
- Chronic urticaria 환자중 1/3에서 보임. 다양한 genetic polymorphism관찰됨.
Urticaria, angioedema, anaphylacsis
Induced by multiple NSAIDs
: atopic pt.에서 호발. Facial angioedema가 가장 흔함.
Induced by single NSAIDs.
: atopic ds. 과거력, 음식, 약물 알레르기 있을 시 호발.
