[나노화학] Nano Hazard

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목차
나노입자란
Companies with something in common
What makes it dangerous?
Potential bio-accumulation of nanoscale particles.

Route of Exposure
Carbon nanotubes may be the new asbestose
What is asbestos?
CNT could pose asbestos-like risks
Toxicity of CNT

Quantum Dots
Toxicity of Quantum Dots
Biocompatible Quantum Dots

Current Strategies
Ligand Exchange
Silanization
Polymer Encapsulation
Biocompatible QDs
Quantum Dots
To Dos
Risk Assesment of Nanotoxicology

미래 나노 정책을 위한 선택사항나노 입자의 유해성 평가의 필요성

본문내용
Potential bio-accumulation of nanoscale particles.


Accumulation of a substance within a species can occur due to lack of degradationor excretion

Many nanoparticles are not biodegradable.

If nanoparticles enter organisms low in the food web, they may be expected to accumulate in organisms higher in the food web.


Very little is understood about possible health
effects of nanoparticle exposure!.


흡입: 호흡기를 통해 흡입된 입자는 염증을 야기하고 조직의 손상을 유발.

피부로의 유입 : 입자는 피부를 통해서도 유입된다. Potential hazards 는 현재 알려져있지 않음.

Ingestion : nanoparticles may cause liver damage. Ingested nanoparticles (i.e. for
oral drug delivery) have been found to accumulate in the liver. Excessive immune/ inflammatory responses cause permanent liver damage.



Asbestos
Asbestos is a highly-fibrous mineral with long, thin, separable fibers.

Properties
heat-resistance, low electrical conductivity, flexibility, and high tensile strength were essential factors


The toxic properties of such fibres are dependent upon a diameter narrow enough to allow inhalation deep into the lung, a length that prevents their removal by macrophages, resistance to dissolution in tissue fluid, and a surface able to cause oxidative damage.