![[세포공학] 세포 불멸화-1](http://images.happyhaksul.com/thumb/450/449348-0001.gif)
![[세포공학] 세포 불멸화-2](http://images.happyhaksul.com/thumb/450/449348-0002.gif)
![[세포공학] 세포 불멸화-3](http://images.happyhaksul.com/thumb/450/449348-0003.gif)
![[세포공학] 세포 불멸화-4](http://images.happyhaksul.com/thumb/450/449348-0004.gif)
![[세포공학] 세포 불멸화-5](http://images.happyhaksul.com/thumb/450/449348-0005.gif)
![[세포공학] 세포 불멸화-6](http://images.happyhaksul.com/thumb/450/449348-0006.gif)
![[세포공학] 세포 불멸화-7](http://images.happyhaksul.com/thumb/450/449348-0007.gif)
![[세포공학] 세포 불멸화-8](http://images.happyhaksul.com/thumb/450/449348-0008.gif)
![[세포공학] 세포 불멸화-9](http://images.happyhaksul.com/thumb/450/449348-0009.gif)
![[세포공학] 세포 불멸화-10](http://images.happyhaksul.com/thumb/450/449348-0010.gif)
![[세포공학] 세포 불멸화-11](http://images.happyhaksul.com/thumb/450/449348-0011.gif)
![[세포공학] 세포 불멸화-12](http://images.happyhaksul.com/thumb/450/449348-0012.gif)
![[세포공학] 세포 불멸화-13](http://images.happyhaksul.com/thumb/450/449348-0013.gif)
![[세포공학] 세포 불멸화-14](http://images.happyhaksul.com/thumb/450/449348-0014.gif)
![[세포공학] 세포 불멸화-15](http://images.happyhaksul.com/thumb/450/449348-0015.gif)
![[세포공학] 세포 불멸화-16](http://images.happyhaksul.com/thumb/450/449348-0016.gif)
![[세포공학] 세포 불멸화-17](http://images.happyhaksul.com/thumb/450/449348-0017.gif)
![[세포공학] 세포 불멸화-18](http://images.happyhaksul.com/thumb/450/449348-0018.gif)
![[세포공학] 세포 불멸화-19](http://images.happyhaksul.com/thumb/450/449348-0019.gif)
![[세포공학] 세포 불멸화-20](http://images.happyhaksul.com/thumb/450/449348-0020.gif)
분야
pptx2.The Main Issue
Immortalization
Normality Test of Immortalized Cell
3.Conclusion
Application
Discussion
4.References
- Telomere structure distinguish double strand
break and linear chromosome.
- Mammalian’s telomere compose of
(5'-TTAGGG-3')n.
- Human’s telomere length : 15-20 kb
- Disappearance 50-200 bp/ one duplication
(the end-replication problem).
no more doublings
(No hTERT)
continuous doublings
(+ hTERT)
2) 박정수, , Journal of The Korean Geriatrics Soci, 2004, 8(1):1-7.
3) 신득용, 세포노화의 분자메커니즘, 1998.
4) 양성렬, , 노인의학1, 2003, 27-40.
5) 최기환 외, ,1999.
6) 최병호, , 2002.
7) 최윤재, , 2006.
8) 최정은 외, 간 : 불멸화된 일차 간세포를 이용한 C형 간염바이러스의 in vitro 배양, 2008.
9) B Hoffman, DA Lie bermann, , Oncogene 27, 6462–6472, 2008.
10) Changwook Lee and Yunje Cho, , Reviews in Medical Virology, 2002.
11) DAN MICHAEL-MICHALOVITZ et al., , JOURNAL OF VIROLOGY, 1991.
12) Girdhar G Sharmal et al., , 2003.
13) Jerry W.Shay, Woodring E.Wright, , Carcinogenesis, 2005, 26:867-874.
14) Jinglan Zhang, , Int J Clin Exp Pathol, 2008
15) John C.Reed, , American Journal of Pathology, 2000, 157.5:1415-1426.
16) Kedar Hastak, , The FASEB Journal, 2005.
17) Lewis J. Kleinsmith, , Pearson Benjamin Cummings, 2006, pp.20-27.
18) LIDIA DE FILIPPIS, , 2007.
19) Ramirez, , 2001.
20) W. S. Klug et al., , 9th edition, 2008
