[PBL] Hypoventilation 증후군(영문)

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레포트 > 의약계열
2010.08.14
10페이지 / hwp
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24원 (구매자료 3% 적립)

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[PBL] Hypoventilation 증후군(영문)에 대한 자료입니다.

Introduction

Background

Pathophysiology

Frequency

Physical

Causes

본문내용

Introduction
Background
The respiratory system serves a dual purpose: delivering oxygen to the pulmonary capillary bed from the environment and eliminating carbon dioxide from the blood stream by removing it from the pulmonary capillary bed. Metabolic production of carbon dioxide occurs rapidly. Thus, a failure of ventilation promptly increases the partial pressure of carbon dioxide measured by arterial blood gas analysis (PaCO2). Alveolar hypoventilation is defined as insufficient ventilation leading to an increase in PaCO2 (ie, hypercapnia). Alveolar hypoventilation is caused by several disorders that are collectively referred as hypoventilation syndromes. Alveolar hypoventilation also is a cause of hypoxemia. Thus, patients who hypoventilate may develop clinically significant hypoxemia. The presence of hypoxemia along with hypercapnia aggravates the clinical manifestations seen with hypoventilation syndromes.Alveolar hypoventilation may be acute or chronic and may be caused by several mechanisms. The specific hypoventilation syndromes that are discussed in this article include central alveolar hypoventilation, obesity hypoventilation syndrome, chest wall deformities, neuromuscular disorders, and chronic obstructive pulmonary disease (COPD). Hypoventilation and oxygen desaturation deteriorate during sleep secondary to a decrement in ventilatory response to hypoxia and increased PaCO2. In addition, diminished muscle tone develops during the rapid eye movement (REM) stage of sleep, which further exacerbates hypoventilation secondary to insufficient respiratory effort.

#PBL #증후군 #Hypoventilation #증후 #영문

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