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분야
pptxHistoplasmosis
Blastomycosis
Coccidiodomycosis
Acquired by inhalation of dust particles from contaminated soil
Markedly resemble Tbc
Macrophages are the major target of infection
Patients with acquired immunodeficiency syndrome are susceptible to disseminated infection with Histoplasma (opportunistic pathogen)
Diagnosis
Culture
Identification of the fungus in tissue lesions.
Serologic tests for antibodies and antigen.
Antigen detection in the body fluids is most useful in the early stages
Blastomycosis
Soil-inhabitating, dimorphic fungus
Remarkably difficult to isolate.
Three clinical forms
Pulmonary blastomycosis
Disseminated blastomycosis
Primary cutaneous blastomycosis
Wikipedia
Class handouts
