소개글
[생화학]Methylation Markers for Small Cell Lung Cancer in Peripheral Blood Leukocyte DNA(영문)에 대한 자료입니다.
목차
1.Methods
2.Results 변인 통제
3.Results 실험 과정
4.Results Pyrosequencing Methylation Assay
5.ResultCpG Methylation Patterns
본문내용
“Differential methylation status in peripheral blood DNA has been linked to risk of several cancers.”
3 major parameters
FDR q values
# of significant CpGs/gene
mean differences among groups
Selection of 9 sites
ROC receiver operation curve 0.858(85.5%)
CSF3R : methylation 5% 감소시 SCLC 4배 증가
ERCC1 : methylation 5% 감소시 SCLC 1.5배 증가