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[제약공학] Stimuli nonsensitive(영문)에 대한 자료입니다.
목차
Stimuli-Sensitive
Polymers
Overview
Before
Introduction
Step 1
Definition
Mechanism
Step 2
Temperature
Step 3
-sensitive polymers
Conclusion
본문내용
Optimum dose
at the right time
in the right location
The polymer which undergo
“property transformation”
swelling
reversible volume phase-transition
sol-gel phase-transition
in response to the
external physicochemical stimuli,
also called phase-transition polymer.
외부자극에 의해 민감하게 반응해
특성(Property)이 변화하는 고분자,
“상전이 고분자”
(phase-transition polymer)
; at certain temperature
-> a volume phase transition
LCST(lower critical solution temp.)
UCST(upper critical solution temp.)
Change in the hydration state
1) volume phase transition
2) coil-to-globule transition
Room temp. -> Body temp.
= change the physical properties
참고문헌
1. 육순홍·조선행·배유한,
2. Chaoliang He, Sung Wan Kim, Doo Sung Lee,
3. Jing Han, Kemin Wang, Dongzhi Yang, Jun Nie,
4. Fenghua Meng, Zhiyuan Zhong, Jan Feijen
5. 온도민감성 하이드로겔의 생성과 주사제 개발, 국제특허분류(IPC9판)A61K-047/34;AA61K-047/30;A61K-047/48, 특허출원번호 10-2007-0067371(2007-07-05)
6. http://m.cafe.naver.com/spectro/863
7. http://chiwu.chem.cuhk.edu.hk/pub/macromolecules/ma-31-2972.pdf