소개글
[생물학] 구제역바이러스(foot and mouth disease virus)(영문)에 대한 자료입니다.
목차
1. General structure and function of FMDV
2. Structure of FMDV
3. Pathogenesis of FMDV
4. Infection cycle of FMDV
5. Vaccine for FMDV
6. Possibility of human infection
본문내용
RNA Virus Picornaviridae
Aphthovirus FMDV
Specified as 7 serotype
(O, A, C, SAT1, SAT2, Sat3, Asia1)
and 80 subtype
Serotype O is most common and current damage was caused by it
21-25 nm nonenveloped capsid virus
Icosahedral capsid structure containing ssRNA
Virus Capsid: made up from 4 encoded proteins (VP1~VP4)
VP1~VP3: capsid shell, VP4: interior surface
VP1: attachment site - most important region
4. pH inside endosome get low
5. VP4(virus’ captid shell) uncoating
release viral genome
6. Cap-independent translation mechanism
Translation initiate