Genetic lesions found in the different thyroid carcinoma subtypes
최근 연구에 따른 분자생물학의 발전에 따라 표적 약물 개발과 치료적 접근에 박차를 가할 수 있게 되었다. 갑상선 암에는 네가지 주요 타입이 있는데, PTC, FTC, ATC, MTC가 그것이다.
PTC는 전체 갑상선암의 80%를 차지하는 것으로 RET 리셉터 티로신키나
Classification of insulin analogues
B. Structure of insulin analogues
C. Starting point of drug therapy
D. Benefit & Specificity
E. Administration of insulin analogues
F. Side Effects of insulin analogues
Coumadin Chloramphenicol
Clofibrate Alcohol Parnate
Ibuprofen Aspirin Sulfinpyrazone
Sulfonamide Ammonium chloride
Diazoxide Rifampin Diuretics
Sodium bicarbonate
drug: PTU, carbimazole, methimazole
-radioiodine: 131I
2. Acute Gastro-Enteritis
-GFS f/u
Thyrotoxicosis is defined as the state of thyroid hormone excess and is not synonymous with hyperthyroidism
But, the major etiologies of thyrotoxicosis are hyperthyroidism caused by Grave’s disease, toxic MNG, and toxic adenomas
2. Pathogenesis (cont.)
Polymorphisms in HLA-DR, CTLA-4, and
(2) Active targeting
Nanoparticle passive targeting can be enhanced by ‘active targeting’, where specific ligands (peptides, antibodies, aptamers, or small molecules) are attached to the nanoparticle surface to bind receptors/antigens overexpressed on cancer cells. Targeting increases accumulation in tumors and lessens exposure to healthy tissue, which can improve a toxic drug’'s therape
A. Limitations
So far we have seen a new approach of using stem cells for targeting cancer site and a new concept of
treatment. However it might seem fascinating, it is important to note that significant impediments remain
before the true potential of this novel therapy can be fully realized. Here in this section we are going to
mainly focus on the limitations of neural stem cells esp