알레르기성 비염
1. Definition
Allergic rhinitis is an IgE mediated hypersensitivity of nasal mucous membrane.
Characterized by sneezing, itching, watery rhinorrhea and a sensation of nasal obstruction.
It may also involve the lining of paranasal sinuses.
Allergic rhinitis occurs in atopic individuals who are exposed to common aeroallergens
2. Incidence
10-20 % of general population.
아토피 피부염을 가진 소아에서 흔함.
6. probiotics나 house dust같은 aeroallergen에 대해서도 아직 논란중.
임상 양상
1. 소얌감과 소파
2. 경과 : 악화와 완호
3. 전형적 병변은 습윤성 피부염
4. 아토피 (천식, 알레르기성 비염, 음식 알레르기 또는 습진)의 병력 또는 가족력
5. 임상경과가 6주 이상 지속됨
AI case presentation
- allergic rhinitis -
What is Allergic rhinitis?
Symptomatic disorder of the nose induced by an Ig-E mediated inflammation after allergen exposure
- Nasal obstruction
- Itching
- Rhinorrhea
- Paroxysmal sneezing
Nasal sx. lasting > 1 hr on most days
Prevalence : 16%(perennial 8%, seasonal 2%, mixed type 6%)
Pathophysiology
Classification
Seasonal Rhinitis
Pollen
Spring (Ma
JOURNAL REVIEW
ATOPIC DERMATITIS
Nancy Wasserbauer, DO, Mark Ballow, MD
BACKGROUND
PATHOPHYSIOLOGY
RISK FACTORS
CLINICAL APPERANCE & DISTRIBUTION
DIAGNOSIS
TREATMENT
CONTENT
BACKGROUND
Atopic dermatitis is
pervasive, chronic, relapsing disease.
10-20% of the pediatric population
1-3% of the adult population
Less than 20% of adults with AD
have the onset of disease after adolescence
EPIDEMIOLOGY
Immunoglobulin E
in health and disease
Basic characteristics of IgE
IgE is the antibody isotype that contains the ε heavy chain and it is a monomer with five domains in the immunoglobulin structure
in plasma
- concentration of less than 1 μg/mL
in serum
- a half-life of about 2 days
Basic characteristics of IgE
IgE binds to its receptor FcεR,
High-affinity receptors (FcεRI)
-wide var