hyperresponsiveness
Obesity
sex
Environmental Factors
Indoor allergens
Outdoor allergens
Occupational sensitizers
Tobacco smoke
Air Pollution
Respiratory Infections
Diet
Identify and reduce exposure to risk factors
Exercise may lead to asthmatic symptoms but patients should not avoid exercise but use beta agonist as prophylaxis instead
Advice patient with moderate to severe asthma to have influe
천식의 치료
* 원인/유발인자를 제거하는 것이 가장 성공적인 치료법
<약물요법>
1. Reliever(bronchodilator)
(1) β2-agonist
*작용기전 : β-adrenergic receptor 자극, G protein 활성화, cAMP 형성
*효과 : relaxation of airway smooth muscle, inhibition of mast cell mediator release,
inhibition of plasma exudation and airway edema, increased mucus secretion
incr
Asthma
Asthma란?
Asthma definition
Chronic inflammatory disorder of airway
Increase in airway responsiveness
Airflow obstruction that is often reversible
유병률(매우흔함) : 선진국 성인 최대 10~12% 소아 15% (후진국은 낮음, 도시화와 관련)
by Harrison 17th
Asthma의 발생기전은 아직 명확히 밝혀지지 않은 부분이 많습니다.
Allergens
Sensitizers
Virus