Update in the Mechanisms of Allergen-Specific Immunotherapy
Introduction
Conclusion
Immune Response To Allergen
Basis of Immunotherapy
Role of Th17 And Th22 Cells On Allergic Disorders
Dendritic Cells As Key Players In Allergic Inflammation
Role of Regulatory T cells In Immune Tolerance To Allergens
Therapeutic Approaches That Use Regulatory T-Cells
Mechanism of Allegen-Specific Immunotherapy
Tre
allergic rhinitis, one of the most common allergic diseases in Korean children. As a cross-sectional study, the findings of this study were based on questionnaire responses. The reliability and validity of the questionnaire were established by previous studies, standardized questionnaires such as ISAAC, and through prior pilot testing. Taking into consideration the comprehensive levels of each
Asthma
Asthma란?
Asthma definition
Chronic inflammatory disorder of airway
Increase in airway responsiveness
Airflow obstruction that is often reversible
유병률(매우흔함) : 선진국 성인 최대 10~12% 소아 15% (후진국은 낮음, 도시화와 관련)
by Harrison 17th
Asthma의 발생기전은 아직 명확히 밝혀지지 않은 부분이 많습니다.
Allergens
Sensitizers
Virus
response
Type IV: delayed T cell mediated response
Small particles deposit in bronchioles
Allergic granulomatous reaction
No increase in IgE or eosinophils
Clinical Presentation
Acute form
4~ 8 hours after exposure
Cough, fever, chill, myaliga, dyspnea, nausea
Bibasilar crackle
Subacute form
Few days after exposure
Exertional dyspnea, cough, fatigue
Chroni