암은 우리나라에서 첫 번째로 흔한 사망원인이며, 환경공해와 스트레스 증가 등 여러 가지 요인으로 인해 암 발생률 또한 해마다 증가하는 추세이다. 암을 진단받은 대상자의 두려움이 5D, 즉 죽음(Death), 기형(Disfigurement), 불구(Disability), 의존성(Dependence), 대인관계의 어려움(Disruption of relationship)으로 표
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80%: cholesterol stones
20%: pigment stones
유병률: 4.25% (서양보다 약간 낮다)
Lack of depth perception
View controlled by camera
operator
More difficult to control
hemorrhage
Decreased tactile discrimination
Potential CO2 insufflation
complication
Adhesions / inflammation
limit use
Slight increase in bile duct
injury
중략.............
Socioeconomic Factors
No significant differences were found between cases and controls on most of the variables.
employment groups (p = 0.029)
meat consumption (p = 0.012)
chicken consumption (p = 0.034)
Malnutrition
세포매개면역을 저하시킨다.
higher point prevalence of infection in undernourished patients or community dwellers
worse and more frequent complications of infect
To make breakthrough progress in the molecular understanding of transcription and its regulation
disturbances in transcriptional regulation contribute cancer, inflammation, heart disease and metabolic diseases.
Essential to be able to direct this development to form only the wanted type of cells
Gene targeting in ES cell
1. ES cell culture
2. Construction of targeting vector
3. ES