Abstract
Abacavir (ABC) is a nucleoside analog reverse trascriptase inhibitor (NRTI) used to treat HIV and AIDS. The pharmacogenetics of abacavir are relate to the human leukocyte antigen B (HLA-B) gene and its variant allele *57:01. This particular allele has been strongly associated with abacavir hypersensitivity. Limited research has been conducted in this area, though some potential exists
50-60% reduction in female to male transmission
Control sexually transmitted infections – reduce co-factors that facilitate transmission
Contaminated blood/needle exposure
IDU – reduce needle sharing, needle exchange programs, drug substitution programs
Screening of transfused blood products
Health care settings – universal precautions, post-exposure prophylaxis
Laboratory Monitoring of Patients with HIV Infection
Patients with CD4+ T cell counts <200/L are at high risk of disease from P. jiroveci, while patients with CD4+ T cell counts <50/L are at high risk of disease from CMV, mycobacteria of the M. avium complex (MAC), and/or T. gondii. Patients with HIV infection should have CD4+ T cell measurements performed at the time of diagnosis and every 3&
I.
1. 문제 제시
35세의 젊은 여자가 2개월 전부터 팔 다리 부종이 나타나고, 전부터 있던 호흡곤란이 악화되어 내원하였다. 1달 전부터 손, 발 피부에 검은 자반이 생겼다고 한다.
2. 단서 인식
- 35세 젊은 여자
- 2달 전부터 팔 다리 부종
- 전부터 있던 호흡곤란 악화
- 1달 전부터 손 발 피부에
FUO 양상의 감염질환
- 결핵, 농양이 가장 흔함
- 그 중 결핵(폐외 결핵, 속립 결핵, 폐결핵) 이 단일 질환 중 가장 흔하다!!!
- 잠복 농양은 최근의 수술환자, 당뇨, 면역 억제자에서 복강 및 골반 내에 발생한다.
FUO 양상의 결체조직질환
-juvenile rheumatoid arthritis (JRA, formerly called Still's disease) in younger pa