(2) Active targeting
Nanoparticle passive targeting can be enhanced by ‘active targeting’, where specific ligands (peptides, antibodies, aptamers, or small molecules) are attached to the nanoparticle surface to bind receptors/antigens overexpressed on cancer cells. Targeting increases accumulation in tumors and lessens exposure to healthy tissue, which can improve a toxic drug’'s therape
Virus is
Small infectious agent that can replicate
only inside the living cells of organisms
Life Properties are
“Organisms at the edge of life“
Do not have their own metabolism
Do not have a cellular structure
Possess genes and evolve by natural selection
Reproduce by creating multiple copies
Assembled within cells
Oncovirus is
Virus that can cause cancer
17.8% hu
cancer staging)가 무엇인지?, 3) 악성종양에 대한 병기를 분류하는 방법 중 TNM 분류방법은 무엇인지에 대해서 구체적으로 설명하시오. (15점) 2. 혈액응고과정의 3단계, 2) 범발성 혈관내 응고증후군(DIC)의 발생기전을 설명하고, 3) DIC 관련 혈액검사, 4) 사용 약물의 약리작용과 부작용, 5) DIC 환자의 간호중재에
13개의 아미노산으로 구성된 짧은 oligonucleotide.
Telomerase의 촉매부위에 대한 친화도와 특이성이 높아서 경쟁적 저해제 역할.
5’end에 붙인 지방사슬 인체의 조직과 세포를 쉽게 투과.
여러 혈액암과 고형암에 뛰어난 항암효과.
항암제 및 방사선 치료에 대한 저항성을 부여하는 암 줄기세포(CSCs) 공
STEP1: ABOUT SKIN CANCER
Cause of cancer _ 2 cases
1.Cell growth doesn’t stop
2.Disorder of apoptosis
p53 : Tumor repressor gene
P53 : transcription factor
Functions
-p53 are that first arrest cell cycle so control cell growth, also active apoptosis suicide program
P53 mutation ->p53 sytem breaks down, it can’t act as Transcriptor factor-> generating tumor