오스트레일리아의 대륙에 처음으로 발을 디딘 사람은 Warramurrungunji라는 여성이다. 그냐는 바다로부터 북오스트레일리아 섬에 나타났고, 내륙으로 향하였으며, 그 과정에서 아이들을 낳고, 각 아이들을 특정 공간에 두었다. 그녀가 들판을 가로질러 이동하며, Warramurrungunji는 각 아이들에게 “나는 너희
History of sulfonylurea
IPTP for typhoid fever(장티푸스) in early 1940s
Many patients died. – acute & prolonged hypoglycemia
Carbutamide
effective oral hypoglycemic
Firtst sulfonyluea hypoglycemic
1. What are anabolic steroids?
(1) Definition and structure of anabolic steroids
Anabolic steroids - or more precisely, anabolic-androgenic steroids are synthetic derivatives of testosterone.
The effects of anabolic-androgenic steroids mimic those of testosterone. Natually synthesized hormones, such as testosterone, are types of lipids. they have a four-ring carbon skeleton and are synthe
action by up-regulating of carnitine palmitoyl transferase(CPT)-1 and acyl CoA oxidase(ACO) which are target enzyme of FA oxidation
It can be considered on that fact that in the WAT expression of PPARα is occurred but in the PPARα -/- condition expression of PPARα mRNA is not occurred.
PPARα+/+
PPARα-/-
Apetite 3
Decreased(32%)
Decreased(37%)
3. Synapse Characteristics
① Presynaptic cell에 신호 도착
② Na+ channel open, Ca+ channel open
③ Ca 이 synaptic vesicle들과 결합
④ vesicle들이 안에 담긴 neurotransmitter들을 synaptic cleft 방향으로 방출
⑤ Neurotransmitter는 receptor에 결합
⑥ postsynaptic cell의 Na channel open
⑦ postsynaptic cell에 depolarization