<심낭염의 종류 및 발생기전, 대동맥류의 분류, 진단 및 치료법>
1. 심낭염의 종류 및 발생기전
(1) Acute Pericarditis
- The most common pathologic process involving the pericardium
- The most common causes are viral infection and unknown (idiopathic).
1) Viral or Idiopathic Form of Acute Pericarditis
- Cause: coxsackievirus A or B, the virus of influenza, echov
①Entry(-> Host cell)
• Adenovirus의 숙주 세포 내로의 진입 시 Virus-host cell 사이의 2가지 interaction 존재
1. Host cell의 Receptor와의 interaction. -> Fiber protein의 knob domain
① CD46 for the group B human adenovirus
② the coxsackievirus adenovirus receptor (CAR)
**MHC1 & Sialic acid
2. The penton base protein then binds to the integrin family.
• 2
Epidemiology and clinical manifestations
Chickenpox
- Rash, low-grade fever, malaise
- Benign to immunocompetent patient
- Skin lesion : Hallmark of infection
maculopapule -> vesicle, scabs
(over hours to days)
Trunk and face -> other areas of the body
- Immunocompromised patients: hemorrhagic based lesion
HSV2
-Symptoms of herpes simplex virus infection include watery blisters in the skin or mucou membranes of the mouth, lips or genitals.
-as neurotropic and neuroinvasive viruses, HSV-1 and -2 persist in the body for the life of the carrier by becoming latent and hiding from the immune system in the cell bodies of nerves.
-After the initial or primary infection, some infected people experienc