of peptide that cause stimulation of target organ should be the same
⑤ The assay must not measure biologically inactive degradation product
⑥ It should be possible to prevent the physiologic response by removing the peptide from the blood or by specific antagonism at its receptor
1.Gastrin
Action
major hormonal stimulant of gastric acid secretion
trophic action to gastric mucosa
gastric acidity 감소
② 이전의 gastric surgery (antrectomy) (15~20년의 잠복기)
③ atrophic gastritis and/or pernicious anemia
④ histamine, H2-receptor antagonists 등의 장기 복용
-알콜은 위암 발생과 관련 없다.
*vitamine A 및 b-carotene : 항산화 촉진 (→위암 발생 ↓)
2)H. pylori 감염
-만성 위염, 위내 산도 감
vascular insufficiency, or in systemic diseases such as diabetes, scleroderma, and amyloidosis. Idiopathic gastroparesis occurring in the absence of systemic illness may follow a viral prodrome, suggesting an infectious etiology. Intestinal pseudoobstruction is characterized by disrupted intestinal and colonic motor activity and leads to retention of food residue and secretions, bacterial overgro