[문헌고찰] - 해부생리
▣ 심장 Heart
? 구조
1) 모양과 크기
① 모양 : 속이 비어있는 원추 모양의 장기(평활근,횡문근)
② 크기 : 평균 14cm 길이 & 9cm 폭
③ 무게 : M - 300g , F - 250g
2) 위치
① with in mediastinum(lateral-lung, anterior-sternum, posterior-vertebrae)
② base : 2nd rib 아래
apex : 5th intercostal space and mid clavian(
Ⅰ. Ischaemic heartdisease
Ischaemic heartdisease
Ischaemic heartdisease (IHD), or myocardial ischaemia, is a disease characterized by ischaemia (reduced blood supply) of the heart muscle, usually due to coronary artery disease (atherosclerosis of the coronary arteries). Its risk increases with age, smoking, hypercholesterolaemia (high cholesterol levels), diabetes, and hypertension (hig
disease
(men <55 years or women 65 years)
(based on Wilson, D'Agostino, Levy et al. 'Prediction of Coronary HeartDisease using Risk Factor Categories', Circulation 1998)
OutcomeCoronary HeartDisease
Duration of follow-upMaximum of 12 years, 10-year risk prediction
Population of interestIndividuals 30 to 74 years old and without overt CHD at the baseline examination
is indicated
It often affects the ascending aorta and aortic arch, causing obstruction of the aorta and its major arteries
Pulseless disease
: frequent occlusion of the large arteries originating from the aorta
The pathology
: panarteritis, characterized by mononuclear cells and occasionally giant cells, with intimal hyperplasia, medial and adventitial thickening
Diseases of aorta
Aortic dissection은 대동맥의 내막이 찢어지고 혈류에 의해 내막과 중막이 박리되면서 false lumen을 만든 것이다. Acute dissection은 심각한 흉통이 있지만, chronic dissection은 별다른 동반 증상이 없다. Ischemic heartdisease의 통증과는 다르게, aortic dissection의 흉통은 갑자기 시작된 극심한(찢어지는 듯