task currently important.
Regulation of nanoparticles.
Size : 10~100nm (EPR effect)
Coating PEG polymer
Why nanoparticles?
1) It can deliver a larger quantity of drugs with better safety.
2) Easy to attach targeting ligands.
3) It is enough size to deliver multi-drugs.
4) Can regulate releasing of drug particles.
5) Can avoid multidrug resistance through cell-surface protein pump.
Heat dissipation이란?
Dissipation
: 소산(消散), 소실, 분해
물질에서 발생하는 열을 효율적으로 분산시켜
빠른 시간 내에 온도를 낮춰 주는 것이 중요
특히 반도체 (ex : 일상 생활에서 가장 많이 쓰이는
CPU(Central Processing Unit)는 고열로 인한
오동작을 방지하기 위한 빠른 열 분산이 필수
1. Nanorods
of the reported procedures for rod formation, seedmediated growth has been by far the most efficient and popular approach. The role played by the seed particle is also critical. Furthermore, the presence of small amounts or silver nitrate during the synthesis has a dramatic effect on the final shape and crystalline structure if the particles. Citrate-capped gold nanoparticle, prepare
nanoparticles that can carry the drug molecules to the target safely.
5.2.2 Nanocarriers - Nanoparticles
Before starting with the functionalization of nanoparticles, it is important to keep in mind a range of useful properties we wish to have in any drug delivery across the BBB(Blood brain barrier). In this context, owing to their small size, customizable surface, improved solubility, tar