cells and are thus interchangeably called urothelial or transitional tumors, but squamous and glandular carcinomas also occur. Here, we discuss the urothelial cell tumors in some detail and only touch on the others.
1. Urothelial (Transitional Cell) Tumors
- These represent about 90% of all bladder tumors and run the gamut from small, benign lesions that might never recur to aggressive cancer
cancercells.
Treated Methanol extracts from Linum usitatissimum and Perilla frutescens to human gastric adenocarcinomacells, human colon adenocarcinomacells, and human hepatocellular carcinomacells
Result
- Methanol extracts from Perilla frutescens showed stronger antimutagenic activity
- Methanol extract from Linum usitatissimum show more effectiveness for growth inhibition of
1.1.2. Cyclooxygenase-prostanoid cascade
Figure 1.1. Metabolism of arachidonic acid
Despite the diverse chemical structure of aspirin-like drugs, the antinociceptive effect of NSAIDs is mainly due totheir common property of inhibiting cyclooxygenases involved in the formation of prostanoids. Prostanoids areformed by most cells and act as autocrine and paracrine lipid mediators. They are n
cell cycle에 있어서 block 기능을 하고 있다고 볼 수 있다. cell cycle은 G1, S, G2, M 단계 이렇게 4단계로 나뉜다. 이중 G1단계에서 S단계로 넘어가는 과정을 control하는 것이 Rb이다. 간단하게 보면 Rb가 cell cycle dependent kinase에 의해 phosphorylation된 상태로 정지되어 있으면 G1단계에 머물러 있게 된다. 하지만 cell growt