of Body Dysmorphic Disorder; preoccupation with drugs in the presence of a Substance Use Disorder; preoccupation with having a serious illness in the presence of Hypochondriasis; preoccupation with sexual urges or fantasies in the presence of a Paraphilia; or guilty ruminations in the presence of Major Depressive Disorder).
E. The disturbance is not due to the direct physiological effects
of nanotechnology
나노물질이 갖는 특유의 성질을 질병의 진단, 치료 등에 사용
Low immunogenicity, good biocompatibility, selective targeting, efficient penetration ofphysiological barrier, less side effect, no surgery required.
DDS란?
: 약물을 효율적으로 전달하여 부작용을 최소화하고 약효를 극대화하기 위한 시스템
DDS의 분류
organ
Voronoi, Russia Doctor, try the first kidney transplant
Hufnagel, German Doctor, transplant kidney to pregnat woman who on the eve of death
Turker who transplanted kidney save his life over 11 month
Pharmaceutical company Sandoz made a innovative Immunosuppressive Drug with mold found in Norway.
It’s CycloSPORINE, strong and few-side effect Immunosuppressive Drug.
1.1.2. Cyclooxygenase-prostanoid cascade
Figure 1.1. Metabolism of arachidonic acid
Despite the diverse chemical structure of aspirin-like drugs, the antinociceptive effectof NSAIDs is mainly due totheir common property of inhibiting cyclooxygenases involved in the formation of prostanoids. Prostanoids areformed by most cells and act as autocrine and paracrine lipid mediators. They are n
of nanoparticles with tumor targeting molecules, such as hormones, growth factors etc. can increase the efficacy of a treatment. Integrin, EGFR are usually the target receptors.
Figure 3 A description of passive and active targeting. Blood vessel near tumor is not well organized, and numbers of pores are found. EPR effect is observed only at the tumor tissue. Through this effect, drugs are a