especially of H chain), estimated to add 3x107 fold to overall diversity.
Recombination signals
Rag-1/Rag-2/Artemis
Non-homologous end joining proteins
defects: Severe Combined
Immunodeficiency (SCID)
Note: SCID can also result from defects that interfere with lymphocyte activation (adenosine deaminase deficiency, purine nucleotide phosphorylase deficiency, MHC defects, etc.)
Introduction of Endostatin
암이란 무엇인가?
발암물질, 바이러스 또는 유전적 변이로 인해
비정상적으로 증식한 세포의 덩어리
생체 내에서의 특징
조절되지 않는 증식
Apoptosis하지 않음
자체적인 혈관생성
혈관 등을 타고
다른 조직으로 이동 가능
암 치료를 위한 연구 방향
최초의 신
Development background
2. History of development
1960s
Discovery of colony-stimulating factors (CSF)
1980s
GM-CSF, M-CSF, G-CSF and multi-CSF
The human G-CSF was cloned
Usage for the treatment at first
1990s
first approval of Filgrastim by the US Food and Drug Administration
Launched Lenograstim
2000s
Launched PEG-filgrastim
Abstract
Bioethanol is one of the alternative sources of oil resources which received attention with biodiesel. Many countries produce bioethanol from food sources such as corn and sugarcane, but it causes food-energy conflicts and farmland problem. So it needs to focus on new biomass which is sustainable, renewable, cost-effective and do not occurred any conflicts. Algae are one of the bioma
유전자 library에는 genomic DNA library와 cDNA library가 있다. genomic DNA library는 어떤 개체가 가진 전체 genome 유전자를 적당한 제한 효소로 처리해서 여러 조각으로 자른 다음에 동일한 삽입 부위를 제공하는 제한 효소로 처리한 벡터에 삽입시켜 놓는 것이고 cDNA library는 reverse transcriptase로 mRNA를 전사하여 cDNA를