Allergic Disease
Increased serum total IgE is not a sensitive test and is of limited clinical value but extreme values may be helpful :
Very low levels(<50ug/L) help exclude atopic disease but not IgE sensitivity to special allergens such as penicillin or Hymenoptera venoms.
If level is >900ug/L, atopic disease is likely but tests for specific allergens are needed.
entire body and is one of the seronegative spondyloarthropathies. Approximately 90% of AS patients express the HLA-B27 genotype, meaning that there is a strong genetic association. However, only 5% of individuals with the HLA-B27 genotype contract the disease. Tumor necrosis factor-alpha (TNF α) and IL-1 are also implicated in ankylosing spondylitis. Autoantibodies specific for AS have not been
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