5.2 Drug Delivery System
5.2.1 Advantage of Nano-drug delivery system
By diagnosis, and for treatment, we need enhanced drug delivery system. Drug delivery system of these days is just eat and let it flow through the body. It is not good at efficiency. Because the digestive system sometimes digest and remove the drug before it reaches to the target.
For enhancing the efficiency of drug
Significantly higher surface area and much narrower pore size distribution in the mesopore region
A large amount of amine-type CO2 capturing agent into its mesopores in a well dispersed manner
Synthesis of MA
PEI impregnation on MA
Amine grafting on MCM-41
Characterization of the materials prepared
CO2 adsorption-desorption measurement
Al(i-PrO)3 (41.68g)+ Alcohol solvent
1. Introduction
혼합 기체 평형 데이터는 흡착형 기체 분리 공정의 설계와 발전에 아주 중요한 요소다. 이런 데이터를 실험으로 일일이 얻기에는 너무 많은 노력과 시간이 필요하므로 단일 성분 흡착등온 데이터에서 혼합기체 흡착평형 데이터를 추측하는 것이 바람직하다. Ruthven(1984), Yang(1987), Tien(1994)
adsorption이 되어 있는 solute와 column으로 가해준 eluting solvent 사이에 equilibrium이 형성된다. Mixture에 포함되어 있는 각각 다른 component들은 stationary, mobile phase에 대한 interaction차이로 mobile phase를 따라 이동하면서 분리가 일어나게 된다. 각각의 component들은 column 바닥에서 떨어지는 solvent drip으로 collection 된다.
1. An engineer performed the following experiment to study the adsorption of benzidine o Filtrasorb 400 granular carbon made by Calgon Corp. Several bottles containing a given concentration of benzidine were prepared; to each a different mass of carbon was added. The suspension was allowed to equilibrate for 2hr; then the carbon was filtered out and the concentration of benzidine was measured; th