drugs are accumulated.
3. Problem and things to be advanced
We cover the meaning of cancer targeting, and how to target cancer. Nowadays, there are many not only drugs but also treatments for cancer treatment, but they have some problems.
1. Chemical-based Anticancer drugs
These chemical-based drugs are systemic drug. Therefore, normal cells are also regarded as cancer cells and beco
1. Introduction
1.1 광역학 반응
Photodynamic reaction(PDT)는 빛, 광민감제, 산소 이 세 가지 요소를 포함한다. 먼저 광민감제 또는 그것의 대사적 전구체를 환자들에게 투여한다. 특정 파장의 빛을 조사하면 광민감제는 낮은 에너지 상태인 ground state에서 높은 에너지 상태인 excited singlet state로 전환된다. 그 다
1.1.2. Cyclooxygenase-prostanoid cascade
Figure 1.1. Metabolism of arachidonic acid
Despite the diverse chemical structure of aspirin-like drugs, the antinociceptive effect of NSAIDs is mainly due totheir common property of inhibiting cyclooxygenases involved in the formation of prostanoids. Prostanoids areformed by most cells and act as autocrine and paracrine lipid mediators. They are n
Recent studies have demonstrated that cyclooxygenase-2 (COX-2) expression is up-regulated in a number of cancers.
The COX-2 isoform is induced in response to inflammatory factors and is expressed in premalignant lesions, including cervical tissues.
In this preliminary study, the variability of COX-2 overexpression in cervical premalignant lesions was assessed.
NSAIDs and COX-2 in
항암제: Carcinostatis substance
anticancer drug
- 악성 종양의 치료를 위하여 사용되는 화학요법(chemotherapy)의 총칭.
항암제를 이용한 암 치료법 : 화학요법(Chemotherapy)
what can chemotherapy do? (화학요법의 목적)
암의 중류와 진행정도(병기)에 따라 화학요법의 목적은 달라진다.
암을 치료하기 위하여
암을 조절하기