slightly thinner and elongated than B-DNA conformation.
The conformational change readily occurs in alternating Purine and Pyrimidine sequence.
Z-DNA is a higher energy conformation than B-DNA (ΔG near +4kcal/mol)
The roles of Z – DNA in biologic system are not clearly identified and an area of active study.
A high affinity Z-DNA Binding Protein , DRADA
hollow cylinders consisti
apparent. Gasoline-Diesel’s 18~23% of average efficiency energy means that most energy is lost with heat loss. Additionally, in case of driving in low speed, the fuel efficiency is very low. On the other hand, enhanced energy efficiency through electronic motor and battery, enabled hybrid car to operate better even in low speed. With much higher energy efficiency, hybrid cars consume less oil,
5.2 Drug Delivery System
5.2.1 Advantage of Nano-drug delivery system
By diagnosis, and for treatment, we need enhanced drug delivery system. Drug delivery system of these days is just eat and let it flow through the body. It is not good at efficiency. Because the digestive system sometimes digest and remove the drug before it reaches to the target.
For enhancing the efficiency of drug
1) 분자의 확산(diffusion)
diffusion이란 분자가 방향성을 지니고 어떤 방향으로 움직이는 것을 말한다. 주로 분자 농도가 높은 쪽에서나 낮은 쪽으로, 혹은 열에너지가 높은 쪽에서 낮은 쪽으로 움직이는 것을 확산이라고 부른다, 분자의 브라운 운동과 비슷하지만 움직임에 방향성과 규칙이 존재하여
잘 표시된다.
k : 속도상수 (rate constant)
A : 상수 (frequency factor)
Ea : 활성화 에너지 (activation energy)
R : 기체상수 (gas constant) T : 절대온도
이러한 표현은 넓은 온도 범위에서 실험과 잘 부합되어 여러 관점으로부터 실제 온