slightly thinner and elongated than B-DNA conformation.
The conformational change readily occurs in alternating Purine and Pyrimidine sequence.
Z-DNA is a higher energy conformation than B-DNA (ΔG near +4kcal/mol)
The roles of Z – DNA in biologic system are not clearly identified and an area of active study.
A high affinity Z-DNA Binding Protein , DRADA
hollow cylinders consisti
polystyrene microplate wells.
② Plate Blocking: addition of irrelevant protein or other molecule to cover all unsaturated surface-binding sites of the microplate wells.
③ Probing/Detection: incubation with antigen-specific antibodies that affinity-bind to the antigens.
④ Signal Measurement: detection of the signal generated via the direct or secondary tag on the specific antibody
Immunoglobulin E
in health and disease
Basic characteristics of IgE
IgE is the antibody isotype that contains the ε heavy chain and it is a monomer with five domains in the immunoglobulin structure
in plasma
- concentration of less than 1 μg/mL
in serum
- a half-life of about 2 days
Basic characteristics of IgE
IgE binds to its receptor FcεR,
High-affinity receptors (FcεRI)
-wide var
Atoms/cm3
Atomic weight
An atom mass
Breakdown field
Binding energy(with Si)
Crystal structure
Density
Solid
Liquid at 1412℃
Dielectric constant, εr
Effective density of states of NC
Effective density of states of Nv
Effective mass, m*/m0
Electrons
Holes
Electron affinity, χ
Energy gap, Eg
Heat capacity
Solid
Liquid at 1,412℃
Index of refraction, n
Intrinsic carrier con