(2) Active targeting
Nanoparticle passive targeting can be enhanced by ‘active targeting’, where specific ligands (peptides, antibodies, aptamers, or small molecules) are attached to the nanoparticle surface to bind receptors/antigens overexpressed on cancercells. Targeting increases accumulation in tumors and lessens exposure to healthy tissue, which can improve a toxic drug’'s therape
A. Limitations
So far we have seen a new approach of using stem cells for targeting cancer site and a new concept of
treatment. However it might seem fascinating, it is important to note that significant impediments remain
before the true potential of this novel therapy can be fully realized. Here in this section we are going to
mainly focus on the limitations of neural stem cells esp
cells
How to think?
Active factor(protein) in ES cells skin cells
Aug, 2006, Pro. Yamanaka ’s laboratory in Kyoto produced ‘pluripotent cells’
Nov, 2007, the first Human iPS cells
iPS cells are a type of pluripotent stem cell
artificially derived from a differentiated cell,
by inducing a “forced” expression of Certain genes!
Mechanism of
cancer pr
cancer)이라 정의한다. 암은 억제가 안 되는 세포의 증식으로, 정상적인 세포와 장기의 구조와 기능을 파괴한다.
(2) 종양 Neoplasia, Tumor
의학적으로는 종양은, 조직의 자율적인 과잉 성장이라고 할 수 있다. 이것은 개체에 있어서 의의가 없거나 이롭지 않을 뿐더러 정상조직에 대해서 파괴적인 것이
cancercells.
Treated Methanol extracts from Linum usitatissimum and Perilla frutescens to human gastric adenocarcinoma cells, human colon adenocarcinoma cells, and human hepatocellular carcinoma cells
Result
- Methanol extracts from Perilla frutescens showed stronger antimutagenic activity
- Methanol extract from Linum usitatissimum show more effectiveness for growth inhibition of