cardiovascular disease
(men <55 years or women 65 years)
(based on Wilson, D'Agostino, Levy et al. 'Prediction of Coronary Heart Disease using Risk Factor Categories', Circulation 1998)
OutcomeCoronary Heart Disease
Duration of follow-upMaximum of 12 years, 10-year risk prediction
Population of interestIndividuals 30 to 74 years old and without overt CHD at the basel
risk of disease in heavily exposed individuals.
Poison : 물질의 종류, 물질의 양에따라
Chemicals may be excreted in urine, feces, or eliminated in expired air, or may accumulate in bone, fat, brain, or other tissues.
Lipophillic drugs and metabolites: transport in the blood by lipoproteins and their penetration through the plasma membrane into cells.
xenobiotics: exogenous
An issue about CHD
Junk food elevates the attack rate of
diabetes and coronary heart disease
Minesota University in America Professor Andrew O. Odegaard
Conducting a survey of Chinese Singaporean
When having fast food more than twice in a week,
the attack rate of diabetes is 27% and the death rate
of coronary disease is elevated 56%
compared with no eating fast food at all.
The prof