안드로겐 무감성 증후군 (Androgen insensitivity syndrome)의 개요, 진단, 감별 진단 질병 및 치료 방법
Ⅰ 개요 (General Discussion)
뮬러관 퇴화나 테스토스테론 형성은 정상 또는 표적 세포에서 안드로겐 작용에 대한 저항으로 남성 발육에 다양한 이상을 초래하게 되는데, 그 중 안드로겐 불응 증후군은 안
Mood is affected by the release of monoamine neurotransmitters including serotonin and norepinephrine.
Lack of neurotransmission at central serotonergic or noradrenergic synapses causes depression.
CRF and depression
Hyperactive HPA axis enhances CRF transmission in the hypothalamus.
Increased arousal, decreased appetite, decreased sexual behavior, and increased heart rate and blood pre
3. Differentiation of Insulin-Producing Cells from Human Neural Progenitor Cells
본 논문은 인간의 뇌에서 얻은 Neural Progenitor Cells을 이용하여 Insulin-Producing Cells로의 분화를 시도한 연구에 대하여 소개하고 있다. 즉, 신경과 관련된 progenitor cell은 신경을 구성하는 세포로 분화되는 것이 일반적이지만 본 논문에서는 특정
Genetic mechanisms are unknown but may be related to a smooth muscle disorder associated with hiatal hernia, reduced lower esophageal sphincter (LES) pressure, and impaired esophageal motility
Considerable morbidity and complications (such as esophageal ulcerations, peptic strictures, and Barrett's esophagus)
Heartburn is the 5th most common gastrointestinal complaint
The 2nd leading o
1. Graves’ disease
-antithyroid drug: PTU, carbimazole, methimazole
-radioiodine: 131I
2. Acute Gastro-Enteritis
-GFS f/u
Thyrotoxicosis is defined as the state of thyroid hormone excess and is not synonymous with hyperthyroidism
But, the major etiologies of thyrotoxicosis are hyperthyroidism caused by Grave’s disease, toxic MNG, and toxic adenomas
2. Pathogenesis (cont.)