1908 - The term "stemcell" was proposed for scientific use by the Russian histologist Alexander Maksimov (1874–1928) at congress of hematologic society in Berlin. It postulated existence of haematopoietic stemcells.
1998 - James Thomson and coworkers derive the first humanembryonic stemcell line at the University of Wisconsin–Madison.
2004–2005 - Korean researcher Hwan
Mid-1800s - Beginning research of Embryo
1908 – ‘StemCell’ from Alexander Maksimov
1963 – Self reproducing cell
1978 – Found Blood stemcell
1981 - Embryonic stemcell
1998 - Human's embryonic stemcell
2001 – First human embryo cloning
(중략)
2.1 Adult StemCell - How?From Bone Marrow
HSCs and MSCs are rich in b
of the body.
* Parkinson’s , Alzheimer’s Disease
* Heart Diseases, Stroke and Diabetes
* Birth Defects
* Spinal Cord Injuries
* Replace Damaged Organs,
Play a major role in cancer
potential for finding treatments and cures
be used to test new drugs
cannot be defined to living things
embryonic stemcells ≠human cloning
question of values
cell을 이용하게 되었다. 또한 신경 줄기세포의 분화 범위는 혈관 세포를 비롯하여 매우 다양하다는 특징과 Type I 당뇨의 근본적인 치료방법을 위한 시도가 증가하고 있는 사회적인 배경 또한 연구의 동기가 되었다.
실험의 과정은 다음과 같았다. 우선 사람의 뇌로부터 얻은 human neural progenitor cell을 in vi
Stemcell calssification
1. Based upon location
Embryonic stemcells
Somatic/ adult stemcells
2. Based upon function
Totipotent
Pluripotent
Multipotent
Unipotent
Reject Response
Traditional Immuno-repressents
Constant administration
Little engraftment after 3~4 weeks
Host immune system impaired
Vulnerable to Infection
↓Need brief immuno-re