Development background
2. History of development
1960s
Discovery of colony-stimulating factors (CSF)
1980s
GM-CSF, M-CSF, G-CSF and multi-CSF
The human G-CSF was cloned
Usage for the treatment at first
1990s
first approval of Filgrastim by the US Food and Drug Administration
Launched Lenograstim
2000s
Launched PEG-filgrastim
What is Amorphous metal?
Polycrystalline grains of varying shapes and sizes
Misaligned planes of atoms slip past each other easily, absorbing energy and allowing dislocations to move, making deformation permanent.
Grain boundaries represent weak spots
Also called Metallic glasses or glassy metals
Cooled faster than atoms can rearrange into a crystal.
Dislocation movement obstructed s
the short
length of the fins laterally, rather than longitudinally down
the long length.
Focused on placing the jets at the end of the fins and using them to induce air flow longitudinally down the length of the fin
The primary jet to emanate directly through the heat sink base and entrain and expel air laterally over the height of the fins through a matrix of synthetic jets
1. 기초적인 조리방법(Cooking Methods)
가열 조리는 식품에 열을 가하는 일로서 먹을 것을 바람직하게 변화시켜서 맛과 영양의 효율 및 안전성을 높이는 것이다. 가열 조리는 조리조작의 중심이 되며, 가열한 다는 것은 식품의 성분이나 물성을 크게 변화시킨다. 주된 변화는 단백질의 열변성, 전분의 점