nudemice. A
therapeutic effect was observed, but it required a 1:2 ratio of NSCs to glioma cells. Another group of
investigators similarly implanted murine glioma cells mixed with murine neural stem cells transduced to
express interleukin-4 into syngeneic hosts, with 80% long-term survival compared with 40% with
nontransduced NSCs and none for controls. Both of these studies involved si
nude fibreglass figures.
Hypnotic atmosphere.
Alex, Pete, Georgie and Dim, teenagers stoned on their milk-plus, their feet resting on faces, crotches, lips of the sculptured furniture.
ALEX (V.O.)
There was me, that is Alex, and my three droogs, that is Pete, Georgie and Dim and we sat in the Korova milkbar trying to make up our rassoodocks what to do with the evening. The Korova Milk Bar sold mi
mice in this house?
Hmm. Everyone has mice.
Mice are everywhere.
See you in the morning, Ruthie.
[Electric Typewriter Clacking]
[Typewriter Motor Shuts Off]
[Turn Signal Clicking]
[Ships Horn Blowing]
[Children Laughing]
Eddie? Eddie?
Mrs. Cole?
Marion.
Come.
You can drive, cant you?
Oh, yeah. Yes I can.
I know boys your age.
They love to drive
every chance they get.
Yes, maam.
But I dont know
ho
Immune surveillance(면역 감시)
“Sensing function “
- T cell : 암세포 감시, 제거
- oncogene의 활성화 or oncogenic event
세포스트레스 상태를 유도
세포노화 or 세포자살 유도
- CD4+ T Cell
세포노화 감지
대식세포가 노화세포를 제거하도록 면역반응 유도
- Th1 cytokine인 IFNγ or TNFα
암세
Cell
FADE IN:
A SPECK OF DUST
Grains of sand dance in the wind. As we glide over a VAST
DESERT, the speck of dust becomes a HORSE AND RIDER.
CATHERINE YOUNG straddles the beautiful black animal, her
mesmerizing eyes scanning the horizon. A curious breeze
blows across her exquisite face and she drinks it in, as if
the wind itself were telling something to her...
Catherine sees a FLICKERING LIGHT