5.2 Drug Delivery System
5.2.1 Advantage of Nano-drug delivery system
By diagnosis, and for treatment, we need enhanced drug delivery system. Drug delivery system of these days is just eat and let it flow through the body. It is not good at efficiency. Because the digestive system sometimes digest and remove the drug before it reaches to the target.
For enhancing the efficiency of drug
Protect underlying tissues from injury: mechanical, heat, cold, biological
Prevent excess water loss
Act as a temperature regulator
Serve as a reservoir for food and water: adipose tissue
Serve as a sense organ for cutaneous senses: pain, heat, cold, pressure, touch
Prevent entrance of foreign bodies: microorganisms.
Epidermis
Keratinocytes, melanocytes
About 0.2mm thickness
Provide v
Protein
Two Major Functions
1) as enzymes
2) as a structural role for the cell
About polypeptide folding and various configurations protein adopt
How several polypeptides associate to form a large unit
The formation and structure of enzyme-substrate complexes and antibodies,
and the models put forth to represent them
1. Peptide bond는 부분적으로 이
CCR5
C-C chemokine receptor type 5, also known as CCR5 or CD195
protein on the surface of white blood cells that is involved in the immune system
the process by which T cells are attracted to specific tissue and organ targets
Many forms of HIV, the virus that causes AIDS, initially use CCR5 to enter and infect host cells
CCR5의 기능
belongs to the beta chemokine receptors family of int
Enamel
√ Hard and white substance covering the teeth
√ The hardest and most highly mineralized
√ Protects the fragile underlying parts of the teeth
√ Covers the crown and supported by dentin
Component of enamel
√ 96% of enamel : mineral, water, organic material
√ contain two unique classes of proteins amelogenins and enamelins
√ The basic unit of enamel is called