COMT Inhibitors
▶ 크롬친화성 세포종 환자에 투여시 고혈압 위기의 위험을 증가
▶ Non-selective MAO inhibitors (phenelzine, tranylcipromine)및
Selective MAO-A,B inhibitors 와는 병용투여 금지.
▶ Cathechol기를 포함한 약물의 대사를 간섭하여 그 작용을 증강시킬 수 있다.
Amantadine
▶ 알려진 연장된 QT간격(Bazett Q
(1) function : line of defense to protect our body
(2) skin is classified to lung
(3) Distinguish Disease with skin color
Disease : acne on face, especially cheek
Facial color : white and have a light red
Attack stage : acne moved forehead to cheek from 2 years ago.
Attack inducement
irregular eating habit
having a taste with instant food.
stress
E. The symptoms are not better accounted for by bereavement, i.e., after the loss of a loved one, the symptoms persist for longer than 2 months or are characterized by marked functional impairment, morbid preoccupation with worthlessness, suicidal ideation, psychotic symptoms, or psychomotor retardation.
4) Criteria for Manic Episode
A. A distinct period of abnormally and persistently eleva
③ Drug and alcohol use
우울증을 일으키거나 악화시키는 대표적인 약물인 reserpine, guanethidine 등은 신경의 저장 granule에서 NE, 5-HT, DA를 고갈시켜 우울증을 일으키는 것으로 알려져 있으며 이밖에 alcohol, amphetamine (withdrawal), anabolic steroids, baclofen, barbiturates, benzodiazepines, β-adrenergic blockers, chloral hydrate, cimetidi
▶ Subtypes of Major Depression
․ Double depression : Dysthymia with a superimposed major depressive episode.
․ Major depression with psychotic features :
Most common psychotic symptom is delusion.
․ Major depression with atypical features : Depression characterized by mood reactivity, in which mood brightens in response to a positive event,
Occlusive aortic disease caused by atherosclerosis
: usually confined to the distal abdominal aorta below the renal arteries
The severity of the symptoms depends on the adequacy of collaterals
With sufficient collateral blood flow
: a complete occlusion of the abdominal aorta may occur without the development of ischemic symptoms.
Acute occlusion in the distal abdomi
1. Graves’ disease
-antithyroid drug: PTU, carbimazole, methimazole
-radioiodine: 131I
2. Acute Gastro-Enteritis
-GFS f/u
Thyrotoxicosis is defined as the state of thyroid hormone excess and is not synonymous with hyperthyroidism
But, the major etiologies of thyrotoxicosis are hyperthyroidism caused by Grave’s disease, toxic MNG, and toxic adenomas
2. Pathogenesis (cont.)