Clinical Trials
Ⅰ. About Clinical Trial.
1. Definition of clinical trials
Although there are many definitions of clinical trials, they are generally considered to be biomedical or health-related research studies in human beings that follow a pre-defined protocol. Observational studies are those in which individuals are observed and their outcomes are measured by the investigators.
2.
신생아 아토피 5세경 40-60% 자연치유
20%가 10대에 자연치유, 65%가 증상완화
정서적 장애나 사회적 장애 유발
아토피성 피부염환자의 반 이상 만성적으로 진행, 재발되는 경향
성장해 가면서 재발 감소, 사지에 국한
환자의 약 반은 다른 알러지 질환을 동반
세균감염에 예민
자주 긁을수록 예후가 나
1. Graves’ disease
-antithyroid drug: PTU, carbimazole, methimazole
-radioiodine: 131I
2. Acute Gastro-Enteritis
-GFS f/u
Thyrotoxicosis is defined as the state of thyroid hormone excess and is not synonymous with hyperthyroidism
But, the major etiologies of thyrotoxicosis are hyperthyroidism caused by Grave’s disease, toxic MNG, and toxic adenomas
2. Pathogenesis (cont.)
Autoimmune hepatitis
Autoimmune hepatitis (AIH) is a disorder of unknown cause characterized by unresolving inflammation of the liver and by the presence of interface hepatitis on histologic examination (Fig. 1-1), hypergammaglobulinemia, and autoantibodies. Diagnosis requires the exclusion of other chronic liver diseases that have similar features, including Wilson disease, chronic viral hep