Abstract
Abacavir (ABC) is a nucleoside analog reverse trascriptase inhibitor (NRTI) used to treat HIV and AIDS. The pharmacogenetics of abacavir are relate to the human leukocyte antigen B (HLA-B) gene and its variant allele *57:01. This particular allele has been strongly associated with abacavir hypersensitivity. Limited research has been conducted in this area, though some potential exists
Virus is
Small infectious agent that can replicate
only inside the living cells of organisms
Life Properties are
“Organisms at the edge of life“
Do not have their own metabolism
Do not have a cellular structure
Possess genes and evolve by natural selection
Reproduce by creating multiple copies
Assembled within cells
Oncovirus is
Virus that can cause cancer
17.8% hu
Morphology
- Virions consist of a capsid.
- Virus capsid is not enveloped, round with icosahedral
symmetry.
- The isometric capsid diameter : 50 nm.
- The capsid shells of virions are composed of multiple
layers.
- Capsids appear round. The capsomer arrangement is
clearly visible.
Replication
- Replication