In this preliminary study, the variability of COX-2 overexpression in cervical premalignant lesions was assessed.
NSAIDs and COX-2 inhibitors show anti-cancer activities in many cancer cells.
Aspirin showed strongest inhibitory effects on viability and survival of YD-8 cells.
Aspirin treatment resulted in severe cell shrinkage and nuclear DNA fragmentation in YD-8 cells.
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properties of cruciferous vegetables, most active isothiocyanate is sulfor-aphane.
Dosage: 500 to 2000mgs daily in divided oral dose.
Sprouts contain 20 to 50 times more sulforaphane in much greater quantity than mature broccoli.
Boiling reduce the levels of anti-cancer compounds in broccoli
Safety - No toxic data available, generally considered safe for appications and as vegetables
active early detection behaviors of breast cancer in outpatients. Korean J Women Health Nurs. 2010 ; 16(2) : 126-36.
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그러나 유방암은 다른 암에 비해 생존율이 비교적 높은 편 Baik OM, Lim JW. Social support in Korean breast and gynecological cancer survivors: comparison by the cancer stage at diagnosis and the stage of cancer survivorship. Korean J Family Social Work. 2011 ;
activated by mechanical trauma, cytokines and growth factors, etc. Conversionof arachidonic acid to prostanoid endproducts is carried out by cyclooxygenases (COX), also known as prostaglandin H synthase (PGHS), at two different sites on the enzyme.
Arachidonic acid is initially cyclized and oxidized to the endoperoxide PGG2 at the cyclooxygenase site of the COX and the product then reduced to a