Differential Gene Expression Common to Acquired and Intrinsic Resistance to BRAF Inhibitor Revealed by RNA-Seq Analysis

( Jun-ho Ahn ) , ( Sung-hee Hwang ) , ( Hyun-soo Cho ) , ( Michael Lee )  한국응용약물학회, Biomolecules & Therapeutics(구 응용약물학회지) [2019] 제27권 제3호, 302~597페이지(총296페이지)

TAG BRAF inhibitor, Drug resistance, Melanoma, RNA-Seq analysis

An Anti-Cancer Drug Candidate CYC116 Suppresses Type I Hypersensitive Immune Responses through the Inhibition of Fyn Kinase in Mast Cells

( Young Hwan Park ) , ( Hyun Woo Kim ) , ( Hyuk Soon Kim ) , ( Seung Taek Nam ) , ( Dajeong Lee ) , ( Min Bum Lee ) , ( Keun Young Min ) , ( Jimo Koo ) , ( Su Jeong Kim ) , ( Young Mi Kim ) , ( Hyung Sik Kim ) , ( Wahn Soo Choi )  한국응용약물학회, Biomolecules & Therapeutics(구 응용약물학회지) [2019] 제27권 제3호, 311~317페이지(총7페이지)

TAG CYC116, Mast cells, Allergy, Immunoglobulin (Ig) E, Fyn, Syk

Deficiency of Sphingosine-1-Phosphate Receptor 2 (S1P₂) Attenuates Bleomycin-Induced Pulmonary Fibrosis

( Soo-jin Park ) , ( Dong-soon Im )  한국응용약물학회, Biomolecules & Therapeutics(구 응용약물학회지) [2019] 제27권 제3호, 318~326페이지(총9페이지)

TAG Fibrosis, Inflammation, Lung, Sphingosine 1-phosphate, S1P₂

Theracurmin Ameliorates Cognitive Dysfunctions in 5XFAD Mice by Improving Synaptic Function and Mitigating Oxidative Stress

( Jihyun Kim ) , ( Jaehoon Kim ) , ( Zhouchi Huang ) , ( Nayeon Goo ) , ( Ho Jung Bae ) , ( Yongwoo Jeong ) , ( Ho Jae Park ) , ( Mudan Cai ) , ( Kyungnam Cho ) , ( Seo Yun Jung ) , ( Soo Kyung Bae ) , ( Jong Hoon Ryu )  한국응용약물학회, Biomolecules & Therapeutics(구 응용약물학회지) [2019] 제27권 제3호, 327~335페이지(총9페이지)

TAG Theracurmin, Alzheimer’s disease, Recognition memory, Spatial memory, Antioxidative activity, Synaptic component

Streptomyces Cytochrome P450 Enzymes and Their Roles in the Biosynthesis of Macrolide Therapeutic Agents

( Myung-a Cho ) , ( Songhee Han ) , ( Young-ran Lim ) , ( Vitchan Kim ) , ( Harim Kim ) , ( Donghak Kim )  한국응용약물학회, Biomolecules & Therapeutics(구 응용약물학회지) [2019] 제27권 제2호, 127~133페이지(총7페이지)

TAG Streptomyces, P450, CYP, Biosynthesis, Macrolide, Secondary metabolite

Integrative Omics Reveals Metabolic and Transcriptomic Alteration of Nonalcoholic Fatty Liver Disease in Catalase Knockout Mice

( Jinhyuk Na ) , ( Soo An Choi ) , ( Adnan Khan ) , ( Joo Young Huh ) , ( Lingjuan Piao ) , ( Inah Hwang ) , ( Hunjoo Ha ) , ( Youngja H Park )  한국응용약물학회, Biomolecules & Therapeutics(구 응용약물학회지) [2019] 제27권 제2호, 134~144페이지(총11페이지)

TAG Catalase, Nonalcoholic fatty liver disease, Liver metabolism, Inflammation, Metabolomics, Transcriptomics

Epicatechin Prevents Methamphetamine-Induced Neuronal Cell Death via Inhibition of ER Stress

( Youra Kang ) , ( Ji-ha Lee ) , ( Young Ho Seo ) , ( Jung-hee Jang ) , ( Chul-ho Jeong ) , ( Sooyeun Lee ) , ( Gil-saeng Jeong ) , ( Byoungduck Park )  한국응용약물학회, Biomolecules & Therapeutics(구 응용약물학회지) [2019] 제27권 제2호, 145~151페이지(총7페이지)

TAG Epicatechin, Methamphetamine, Neuroprotection

Neuroprotective Effects of 6-Shogaol and Its Metabolite, 6-Paradol, in a Mouse Model of Multiple Sclerosis

( Arjun Sapkota ) , ( Se Jin Park ) , ( Ji Woong Choi )  한국응용약물학회, Biomolecules & Therapeutics(구 응용약물학회지) [2019] 제27권 제2호, 152~159페이지(총8페이지)

TAG Multiple sclerosis, Experimental autoimmune encephalomyelitis, 6-Shogaol, 6-Paradol, Astrogliosis, Microglia

Schisantherin B Improves the Pathological Manifestations of Mice Caused by Behavior Desperation in Different Ages-Depression with Cognitive Impairment

( Mengjie Xu ) , ( Feng Xiao ) , ( Mengshi Wang ) , ( Tingxu Yan ) , ( Huilin Yang ) , ( Bo Wu ) , ( Kaishun Bi ) , ( Ying Jia )  한국응용약물학회, Biomolecules & Therapeutics(구 응용약물학회지) [2019] 제27권 제2호, 160~167페이지(총8페이지)

TAG Schisantherin B, FST, Depression, GLT-1, Cognitive impairments

Effects of Intraperitoneal N-methyl-D-aspartate (NMDA) Administration on Nociceptive/Repetitive Behaviors in Juvenile Mice

( Seonmin Kim ) , ( Do Gyeong Kim ) , ( Edson Luck Gonzales ) , ( Darine Froy N. Mabunga ) , ( Dongpil Shin ) , ( Se Jin Jeon ) , ( Chan Young Shin ) , ( Taejin Ahn ) , ( Kyoung Ja Kwon )  한국응용약물학회, Biomolecules & Therapeutics(구 응용약물학회지) [2019] 제27권 제2호, 168~177페이지(총10페이지)

TAG Stereotypy, Tail Licking/Biting, Nociception, Repetitive Behavior, E/I Imbalance

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