[PBL]골다공증 치료
![[PBL]골다공증 치료-1](http://images.happyhaksul.com/thumb/460/459636-0001.gif)
![[PBL]골다공증 치료-2](http://images.happyhaksul.com/thumb/460/459636-0002.gif)
![[PBL]골다공증 치료-3](http://images.happyhaksul.com/thumb/460/459636-0003.gif)
![[PBL]골다공증 치료-4](http://images.happyhaksul.com/thumb/460/459636-0004.gif)
분야
hwpⅡ. 골다공증의 치료
1. Hormone Replacement Therapy
2. Bisphosphonates
3. Calcitonin
4. Selective Estrogen Receptor Modulator
5. Parathyroid hormone
6.Anabolic steroids
7.Thiazides
8.Others
1) Exercise & Life style modification
Exercise
not clearly defined
½ hour 체중부하운동/day
lifetime leisure exercise; associated w/ higher BMD
Stop smoking
Limited alcohol drinking
2) Nutrition and calcium supplementation
Calcium
recommended doses; 1 ~ 2 g/day (childhood; 1~1.2 g/d)
Ca carbonate; inexpensive, well absorbed w/ meals
Ca citrate; better absorbed in fasting
24시간 뇨 calcium 100~250mg로 유지하도록 용량 조절
Vitamin D
increases intestinal Ca. absorption & inhibit PTH secretion
recommended doses; 400~ 800 U/d (10~20 g/d)
calcifediol (25(OH)D3); 20 & 50 g
calcitriol (1,25(OH)2D3); 0.25 g
cholecalciferol (D3); 400 IU
alphcalcidol (1(OH)D3 ); 0.5 g
Ca & Vt. D;
→ increase bone mass, decrease bone loss
→ decrease incidence of fractures
