1.1.2. Cyclooxygenase-prostanoid cascade
Figure 1.1. Metabolism of arachidonic acid
Despite the diverse chemical structure of aspirin-like drugs, the antinociceptive effect of NSAIDs is mainly due totheir common property of inhibiting cyclooxygenases involved in the formation of prostanoids. Prostanoids areformed by most cells and act as autocrine and paracrine lipid mediators. They are n
1.1 Study Designs
․Retrospective Studies
․Prospective Studies
※ Survival Analysis
; Deals with analysis of data that have "time to an event".
※ Survival time
; Time until an event occurs.
※ Event
; a. relapse of a disease
b. death
c. response to a treatment
; Economical,
To obtain answers quickly because the cas
Recent studies have demonstrated that cyclooxygenase-2 (COX-2) expression is up-regulated in a number of cancers.
The COX-2 isoform is induced in response to inflammatory factors and is expressed in premalignant lesions, including cervical tissues.
In this preliminary study, the variability of COX-2 overexpression in cervical premalignant lesions was assessed.
NSAIDs and COX-2 in
1. 이론
(1) 실험 목표
이번 실험은 Inverted Pendulum의 제어에 관한 것이다. arm, Pendulum, Rotary encoder, DC motor로 구성되어 있는 Inverted Pendulum을 수직 방향으로 세워져 유지될 수 있도록 arm을 회전하며 균형을 잡는 것이 최종 목표이다. 이를 위해 운동방정식을 세우고 회로를 구성하며 Rotary encoder, DC motor간의