Laboratory Monitoring of Patients with HIV Infection
Patients with CD4+ T cell counts <200/L are at high risk of disease from P. jiroveci, while patients with CD4+ T cell counts <50/L are at high risk of disease from CMV, mycobacteria of the M. avium complex (MAC), and/or T. gondii. Patients with HIV infection should have CD4+ T cell measurements performed at the time of diagnosis and every 3&
나) 폐에서 surfactant의 역할을 설명하시오.
Type II 폐포상피세포에서 분비되는 surfactant는 폐포 내의 표면장력을 감소시켜 작은 압력으로도 폐포가 열리도록 하며 폐포의 크기에 따라 표면장력을 변화시킴으로써 폐포의 확장을 유지시킨다.
Surfactant 는 표면장력을 감소시켜 줌으로서 폐가 쉽게 확장할
hospitalization, and death. (Lack of resources)
Nirmatrelvir : severe acute respiratory syndrome coronavirus 2 main protease (Mpro) inhibitor with potent pan–human-coronavirus activity in vitro.
Ritonavir low dose 100mg (CYP3A inhibitor) : Enhancing nirmatrelvir pharmacokinetics (approximately five to six times in vitro 90% effective concentration of nirmatrelvir)