소개글
[화학공학실험] synthesis of nitrobenzene(영문)에 대한 자료입니다.
목차
1.Objective
2.Introduction & Background
3.Experimental
Apparatus and Reagents
Procedures
Notices
4.Reference
본문내용
Synthesize nitrobenzene by nitration of benzene with mixed acid as one of the EAS’s example
Understand basic operation of concussion mixing, heating, cooling, and drying liquid.
Electrophile
a reagent attracted to electrons that participates in a chemical reaction by accepting an electron pair in order to bond to a nucleophile.
A example of electrophiles
- Lewis acids
(Because electrophiles accept electrons)
Substitution reaction
a functional group in a particular chemical compound is replaced by another group.
Place 34ml of concentrated nitric acid in a 500 ml Round Bottomed 3 Neck Flask, and slowly shaking for cooling.
Add slowly 40ml of concentrated sulfuric acid.
Place a thermometer in this nitrating mixture, and then add very slowly 36ml of benzene. after each addition, the contents of the flask thoroughly mixed* This should be added about 3ml at a time,* The temperature of the mixture must not be allowed to rise above 50’C, and should be kept under control if necessary by immersing the flask in cold water.
참고문헌
http://en.wikipedia.org/wiki/Electrophilic_aromatic_substitution
http://en.wikipedia.org/wiki/Electrophile
http://en.wikipedia.org/wiki/Liquid-liquid_extraction
http://ko.wikipedia.org/wiki
http://kowon.dongseo.ac.kr/%7Eccpark/root/frame/or_frame08_ob.htm
http://www.chemguide.co.uk
http://www.waterbath.net/types.html
John McMurry Organic Chemistry 2nd Ed.
Organic Chemistry 4th edit, Brown Foote Inverson, 2005, p858-861