Review of systems
Urogenital
Dysuria (-), Frequency (-), Nocturia (-)
Urgency (-), Oligouria(-), Hematuria (-)
Musculoskeletal
Muscle or joint pain (-), Limitation in motor activity (-)
Backache (-)
Skin
Rashes (-), Eruption (-), Jaundice (-), Itching (-), Lumps (-), Changes in hair or nails (-)
General status
V/S
BP : 110/80mmHg – PR : 64/min – RR : 20/mi
protein P2
Location
Human chromosome 7
7q31, at the SPCH1 locus
FOXP2 orthologs are in all mammals
Require for proper brain and lung development
Mutation of FOXP2
Cause a severe speech and language disorder (Human)
Study of mice and songbirds
Differences of FOXP2 between Human and Animals
Chimp : 2 Amino Acids
Mouse : 3 Amino Acids
Zebra finch : 7 Amino Acids
Neanderthal : Same Versi
The purpose of the present study was to determine the role of RhoA prenylation in the activation of RhoA and in the maintenanace of the basal and stimulated (by U-46619) state, before and after prenylation inhibitor GGTI-297.
We also determined cellular distribution of RhoA and ROCK activity. For comparison, we used phasic rectal smooth muscle (RSM).
GGTaseI (=prenyltransferase) : Catalyz
We have shown that in colonic smooth muscle, PKC-α and RhoA translocate and associate with each other in the particulate fraction in response to stimulation with acetylcholine.
We have also shown that RhoA interacts directly with PKC-α in vitro.
1) In human endothelial cells, activation of ROCK by RhoA requires PKC activation .
(1998,Hippenstiel S et al)
2) We have recentl
예로 들 수 있다. 이러한 여러 가지 이유로 지질 산화가 어떻게 조절되고 무엇이 관여하는지가 중요하다. 의미를 보자면, 격렬한 무산소 운동을 하면 근육세포가 white muscle이 되어 비대해지고, 지속적인 유산소 운동을 하면 근육세포가 red muscle이 되어 지구력을 가지게 된다는 상식의 원리를 설명한다.
UCP homologous
Uncoupling protein
Anion carriers in mitochondrial inner membrane
‘Proton leak’으로 화학삼투에너지가 열에너지로 전환된다
5 동형체(homologous)
Thermogenesis in brown adipose tissue(BAT)
How UCP1 work in ETC
…그렇다면 다른 UCP들은 어떤 기능을 할까?
UCP의 다른 생리적 기능
UCP를 통한 충분한 열 생성을
A. Parts of Your Body
1. ears 2. hands 3. nose 4. mouth 5. feet 6. hip 7. breast가슴
B. Inside Your Body (신체내부)
1. lung폐 2. stomach위 3. heart심장 4. muscle근육 5. kidneys신장 6. intestines창자 7. brian 뇌 8. liver간 9. throat목구멍 10. blood vessels혈관
C. Head (머리)
1. hair머리털 bald head대머리 2. forehead이마 3. eyebrow눈썹 4. mustache콧수