(D) 접촉의존성 신호전달은 인접한 세포막 사이의 직접적인 접촉을 필요로 한다. 동일 종류의 신호전달 물질이 내분비, 국소분비, 그리고 신경세포의 신호전달과정에 사용되지만, 결정적인 차이는 표적에 전해지는 신호의 속도와 선택성에 있다.
6.신호전달 물질의 예
몇가지 호르몬과 국소
5.2 Drug Delivery System
5.2.1 Advantage of Nano-drug delivery system
By diagnosis, and for treatment, we need enhanced drug delivery system. Drug delivery system of these days is just eat and let it flow through the body. It is not good at efficiency. Because the digestive system sometimes digest and remove the drug before it reaches to the target.
For enhancing the efficiency of drug
Translocation Melanosome
From Melanocyte to Keratinocyte
Mode of melanin transfer
Membrane Fusion
Vesicular Transfer
Phagocytosis
Phagocytosis
Cytophgocytosis
g/mol. The DNA sequence for the protein was determined by Friedman in 1994 and was found on the obese (ob) gene [4]. The leptin receptor, the molecular structure on the cell surface that binds with leptin, is encoded by the diabetes (db) gene.
Leptin is a 16-kD protein that plays a critical role in the regulation of body weight by inhibiting food intake and stimulating energy expenditure. Defe
Clozapine ?
Clozapine : antipsychotic drug
최초의 비전형적(Atypical) 항정신병 약물
추체외로 증후군 (Extrapyramidal symptoms) X
항 정신병 약물의 대표 부작용
운동능력 소실 등
변연계 도파민 수용체에 특이적
Mechanism of action
아드레날린성, 세로토닌성, 히스타민성 및 콜린성 수용체 등에 길항
Pharmacokinetics (AD