implanted murine glioma cells mixed with murine neural stem cells transduced to
express interleukin-4 into syngeneic hosts, with 80% long-term survival compared with 40% with
nontransduced NSCs and none for controls. Both of these studies involved simultaneous inoculation of
tumor and NSCs with a high NSC/tumor cell ratio, therefore an artificial and nonclinically translatable
strategy.