(1) no effective treatment
(2) lung transplantation
(3) smoking cessation
7) 예후
Factors influencing progression
① cumulative exposure to asbestos
② duration of exposure
③ type of asbestos exposure
3. 탄광부 진폐증 (Coal Worker's Pneumoconiosis)
1) 석탄분진을 흡입하여 발생
2) simple : opacity < 1 cm
과민성 폐장염
inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts. Sufferers are commonly exposed to the dust by their occupation or hobbies.
1.정의
inhalation of an antigen.
This leads to an exaggerated immune response (hypersensitivity).
Type III hypersensitivity and type IV hypersensitivity occur in hypersensitivity pneumonitis
2.기전
1)t
Histoplasmosis
Acquired by inhalation of dust particles from contaminated soil
Markedly resemble Tbc
Macrophages are the major target of infection
Patients with acquired immunodeficiency syndrome are susceptible to disseminated infection with Histoplasma (opportunistic pathogen)
Diagnosis
Culture
Identification of the fungus in tissue lesions.
Serologic tests for antibodies and antigen.
inhalant allergen은 pollen, dust mite, pet의 urine등에서 나온 단백질을 둘러싸고 있다. 이 입자의 크기가 클수록 bronchial tree에 접근하기가 어려운데, 따라서 상대적으로 입자가 큰 pollen이 nasal filter에 걸러져서 rhinitis를 유발하는 것이다.
allergen이 적어도 두 개 이상의 IgE와 만나면 mast cell은 granule을 방출한다.
inhales deeply--
this is a man who loves his walks.
He pulls a piece of toast from his pocket and starts to
nibble as he presses up on the ridge...
??
Low angle: nursing home and ridge beyond
??
...and we see Paul from a distance, just a speck trudging up
toward the treeline. A PICKUP TRUCK rumbles into frame and
parks, a bumper sticker looming large: "I Have Seen God and
His Name Is Newt Gingric