with natural peptide
④ Circulating concentration of peptide that cause stimulation of target organ should be the same
⑤ The assay must not measure biologically inactive degradation product
⑥ It should be possible to prevent the physiologic response by removing the peptide from the blood or by specific antagonism at its receptor
1.Gastrin
Action
major hormonal stimulant ofgastric ac
● Definition of plasma
Plasma is one ofthe four fundamental states of matter, along with solid, liquid, and gas. It is an ionized gas consisting of a collection of charged particles, including ions, electrons, and neutral atoms or molecules. Plasma can be found naturally in the universe in the form of stars, lightning, and auroras, but it can also be artificially created and controlled for
Introduction (What is plasma?)
1. Definition of plasma
Plasma is one ofthe four fundamental states of matter, along with solid, liquid, and gas. It is an ionized gas consisting of a collection of charged particles, including ions, electrons, and neutral atoms or molecules. Plasma can be found naturally in the universe in the form of stars, lightning, and auroras, but it can also be artif
Enamel
√ Hard and white substance covering the teeth
√ The hardest and most highly mineralized
√ Protects the fragile underlying parts ofthe teeth
√ Covers the crown and supported by dentin
Component of enamel
√ 96% of enamel : mineral, water, organic material
√ contain two unique classes of proteins amelogenins and enamelins
√ The basic unit of enamel is called
1.1.2. Cyclooxygenase-prostanoid cascade
Figure 1.1. Metabolism of arachidonic acid
Despite the diverse chemical structure of aspirin-like drugs, the antinociceptive effect of NSAIDs is mainly due totheir common property of inhibiting cyclooxygenases involved in the formation of prostanoids. Prostanoids areformed by most cells and act as autocrine and paracrine lipid mediators. They are n